(NaturalNews) Proteolytic enzymes are specific enzymes that metabolize protein. These enzymes are naturally produced by the human body and other living organisms and help carry out essential functions. Supplementing with these enzymes has shown to have a favorable anti-inflammatory effect on the tissues of the body. A unique enzyme named serratiopeptidase is now emerging as one of the most potent anti-inflammatory supplements.
Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15. This enzyme makes its inhabitants in the intestine of the silkworm. Silkworms go through a transformational process within a cocoon that turns them into moths. It is this specific enzyme that is used by the silkworm to dissolve the cocoon and reemerge as a moth.
Serratiopeptidase has powerful anti-inflammatory properties and is particularly useful for post-traumatic swelling, fibrocystic breast disease and bronchitis. It is able to digest dead tissue, blood clots, cysts, and arterial plaques. Clinical studies have shown it to be effective at reducing swelling and edema and metabolizing scar tissue in the body.
A 2003 study found that 30mg of serratiopeptidase was effective at loosening and reducing mucous build-up in respiratory pathways. This was credited to its ability to reduce the neutrophil white blood cell numbers and to improve the viscoelasticity of the sputum in patients with chronic airway disease.
Serratiopeptidase is also renowned for its ability to reduce pain by blocking the release of pain-inducing molecules from inflamed tissues. There are no known side effects with this. The most common pain-reducing aids are aspirin, ibuprofen and acetaminophen, which are called non-steroidal anti-inflammatory drugs (NSAID`s). These drugs are known to deplete renal and hepatic glutathione and to deplete the body of critical B vitamins and trace minerals leading to stomach, kidney, liver and heart problems.
A 2008 study compared Serratiopeptidase and its anti-inflammatory activity with 2 human pancreatic proteolytic enzymes (trypsin and chymotrypsin) and aspirin. Although all groups were effective at reducing inflammation, serratiopeptidase was the most effective. (6) It was also proven to be effective at reducing swelling and pain intensity in individuals with carpel tunnel and sprained ankles.(7-8) Other studies have shown similar anti-inflammatory effects after oral surgery was performed.(9)
A 2006 study looked at the role serratiopeptidase has on improving immunity. This experimental animal study involved implanting a biofilm-forming bacteria (Staphylococcus epidermis) into a group of rats. The group given serratiopeptidase was highly effective at eliminating this infection. The researchers credited the antibiofilm properties of this specific enzyme as being the key factor. It is also hypothesized that this enzyme may be used to make antibodies more effective. (10)
Serratiopeptidase has been used in Europe and Asia for over 30 years. It is still relatively new in the United States and Canada. Most experts agree that more research is needed with this enzyme; however, the preliminary results look very promising. Many supplement manufacturers are beginning to use this compound with outstanding results. Serratiopeptidase appears to be a major player in anti-inflammatory protocols of the future.
[Editor`s Note: NaturalNews is strongly against the use of all forms of animal testing. We fully support implementation of humane medical experimentation that promotes the health and wellbeing of all living creatures.]
1.Mazzone A, Catalani M, Constanzo M, Drusian A, Mandoli A, Russo S, Guarini E, Vesperini G. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngolog pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990,18(5):379-88
2.Mazzone A, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngolog pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990,18(5):379-88
3.Aso T, et al. Breast engorgement and its treatment: Clinical effects of Danzen, an anti-inflammatory enzyme preparation. The world of Obstetrics and Gynecology (Japanese). 1981;33:371-9
4.Nakamura S, Hashimoto Y, Mikami M, Yamanaka E, Soma T, Hino M, Azuma A, Kudoh S. Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease. Respirology. 2003 Sep;8(3):316-20.
5.Majima Y, Inagaki M, Hirata K, Takeuchi K, Morishita A, Sakakura Y. The effect of an orally administered proteolytic enzyme on the elasticity and viscosity of nasal mucus. Arch Otorhinolaryngol. 1988; 244(6): 355-9.
6.Viswanatha Swamy AH, Patti PA. Effect of some clinically used proteolytic enzymes on inflammation in rats. Indian J Pharm Sci. 2008 Jan;70(1):114-7.
7.Panagariya A, Sharma AK. A preliminary trial of serratiopeptidase in patients with carpal tunnel syndrome. J Assoc Physicians India. 1999 Dec;47(12):1170-2.
8.Esch PM, Gerngross H, Fabian A. [Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase– a prospective study]. Fortschr Med. 1989 Feb 10;107(4):67-8, 71-2.
9.Al-Khateeb TH, Nusair Y. Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. Int J Oral Maxillofac Surg. 2008 Mar;37(3):264-8. Epub 2008 Feb 12.
10. Mecikoglu M, Saygi B, Yildirim Y, Karadag-Saygi E, Ramadan SS, Esemenli T. The effect of proteolytic enzyme serratiopeptidase in the treatment of experimental implant-related infection. J Bone Joint Surg Am. 2006 Jun;88(6):1208-14.
About the author
Dr. David Jockers owns and operates Exodus Health Center in Kennesaw, Ga. He is a Maximized Living doctor. His expertise is in weight loss, customized nutrition & exercise, & structural corrective chiropractic care. For more information go to www.exodushc.com To find a Maximized Living doctor near you go to www.maximizedliving.com